English

Cervical cancer is caused by high risk subtypes of the human papillomavirus. Prophylactic vaccination is not the standard of care in many countries, and where approved, implementation is far from complete. Once infected, prophylactic vaccines no longer prevent the development of cervical cancer, which can only be treated with surgery, chemotherapy or radiotherapy. With an estimated impact of almost 500,000 new cases of cervical cancer and 274,000 deaths per year worldwide, the need for an effective therapy to treat recurrent/metastatic cervical cancer is extremely high. IMMUNISA facilitates a multidisciplinary collaboration between leading European clinical sites specialised in cervical cancer, a partner providing excellent regulatory service and a cutting-edge biotech enterprise to find an effective targeted immunotherapy approach to induce an immune response directed at the tumour.

 

IMMUNISA proposes the use immunotherapeutic platform of Synthetic Long Peptides to mediate dendritic cell antigen expression, resulting in robust T-cell responses against the cancer. In a multi-centre randomised Phase II clinical trial, IMMUNISA will investigate if a vaccine in combination with chemotherapy can prolong the progression free survival rate of people with cervical cancer. The project will run from December 2017 to December 2022.

 

ECPC’s Role

The European Cancer Patient Coalition ensures the project’s compliance with the needs of the people with cancer and is involved in the work package responsible for project management and dissemination. ECPC also promotes project findings to all its Members through the monthly newsletter, the website and social media platforms.

 

Contact Details

ECPC: info@ecpc.org

Funding

IMMUNISA is funded by Horizon 2020: the European Union Framework Programme for Research and Innovation, Project N° 731623.